Stimulating supplement that increases physical capacity and mental concentration, while reducing the feeling of fatigue. In addition, caffeine can help mobilize fat as a source of energy during training.

Caffeine has been one of the most studied bioactive compounds today. Not only in the field of body aesthetics, where several studies have determined that its effect could be related to the increase in the basal metabolic rate and therefore could favor the reduction of body fat during hypocaloric programs. On the other hand, there is also research whose results support that caffeine has ergogenic effects in various sports, such as those of high intensity; therefore, in this installment I will be mentioning several of these phenomena... continue reading
CAFFEINE contains 200 mg of caffeine per capsule, which provides the dose accepted by international sports nutrition societies for amateur and elite athletes. can increase their sports performance and increase concentration levels during training, in addition to benefiting from the increase in fat oxidation processes during physical exercise.
This supplement is a powerful stimulant that will provide you with great energy without calories , necessary for sports practice without affecting the diet. In fact, caffeine is capable of increasing physical fitness and mental concentration, while decreasing the feeling of fatigue.
CAFFEINE is used to speed up the body, thereby increasing energy consumption to finally end up losing fat, that is, having the ability to make the body produce energy allowing increased physical performance. Due to its addictive nature and undesirable effects on the body, caffeine should be administered progressively as long as there are no adverse effects.
These effects have been suggested by studies that show that the use of caffeine (whether in tablet form or not) causes a decrease in the feeling of fatigue and an increase in attention span. That is why these capsules are commonly used by students preparing for their exams and by people who work or drive long hours.
It is important to know the beneficial properties of caffeine:
+ Stimulant: It helps you overcome fatigue, since caffeine stimulates the body in general.
+ Analgesic: relaxes the muscles, which allows you to tolerate muscle pain, back pain, and even headaches.
+ Antioxidant: eliminates free radicals that cause degenerative diseases, such as cancer.
+ Digestive: in low doses, caffeine increases digestive juices and bile helps improve digestion. Ideal for lazy stomachs.
+ Diuretic: caffeine is used as a remedy for obesity treatments because it prevents fluid retention.
Caffeine acts on the central nervous system, produces vasoconstriction, affects the cardiovascular, respiratory and gastrointestinal systems. It also acts at the muscular level and in lipolysis. Contributes to improve performance. The ergogenic effects are explained from the saving of muscle glycogen to the increase in muscle contractibility. Its function is to stimulate the secretion of adrenaline that increases the mobilization of fatty acids, which increases the oxidation of fats to the benefit of saving muscle glycogen.
It is an alkaloid found in certain plants, notably in Camellia sinensis, coffea sp., Theobroma cacao L.Caffeine is a substance produced by these plants with a protective function (repels insects). In principle, it is an agent that arouses attention, activator of fatty acids, which contains a substance belonging to the group of methylxanthines, which in caffeine is It is found in the form of 1,3,7 trimethylxanthine, which acts in the human organism as a stimulant of the central nervous system and cardiovascular function.

Chemical Structure of 1,3,7-trimethylxanthine or Caffeine
As a pharmacological agent, the administration of high doses of caffeine stimulates the activity of the nervous system, increases the elimination of fluids through urine, enhances work heart, increases vasodilatation, dilation of the bronchi and gastric secretions. Biochemically, it is considered an antagonist of A1 and A2 adenosine receptors, a phosphodiesterase inhibitor, and a central nervous system stimulant, which affects the cardiovascular system and produces diuresis. Its actions are similar to those of theophylline, but less potent.
Caffeine administration has been shown to increase basal energy metabolism in a dose-dependent manner in healthy and overweight adult humans. Despite the conflicting data currently being presented, it has been generally accepted that caffeine effectively stimulates the central nervous system and increases basal metabolism in humans.
In general terms, caffeine consumption has been characterized as increasing sports performance during high-intensity cycling in humans, athletics, and other aerobic endurance sports, which is why it is also considered an ergogenic aid in certain types of disciplines (Kreider, et al. 2010), and although it is currently not on the list of prohibited substances by WADA, it is part of the monitoring program carried out by this anti-doping organization. Caffeine acts directly on skeletal muscle, allowing increased transmission of neuronal stimulation, particularly at the motor neuron-muscle junction, blocks adenosine receptors in the central nervous system, interrupting fatigue during aerobic exercise in humans and animals, and decreases concentrations K+ muscles during high-intensity intermittent exercise, as shown by Mohr et al. (2011).
In summary:
• Increases athletic performance during high-intensity cycling, running, and other aerobic endurance sports (Kreider RB, et al. 2010).
• Increases transmission of neural stimulation particularly at the motor neuron-muscle junction (Franco FS, et al. 2011).
• It blocks adenosine receptors in the central nervous system, interrupting fatigue during aerobic exercise (Mohr M, et al. 2011).
• Increases metabolic rate (≈ 4%), from 50 to 200 Kcal per hour immediately after ingestion. The effect is time-dependent and the metabolic rate seems to return to base values ​​after 6 hours of consumption (Vaughan RA, et al. 2014).
By crossing the blood-brain barrier, caffeine acts as an antagonist at A1 and A2 adrenergic receptors, which stops the inhibitory effect of adenosine on the central nervous system. As the brain is stimulated, more dopamine, norepinephrine, and glutamate (stimulating neurotransmitters) are released.
Ingredients: Caffeine, 200 mg; Bulking Agents (Maltodextrin and Microcrystalline Cellulose), Anti-Caking Agents (Magnesium Stearate and Silicon Dioxide), Glazing Agent (Gelatin), Colorants: E-102 and E-171.

Per capsule: 200 mg Caffeine
Energy Value: 0 Kcal
Carbohydrates: 0 grams
Proteins: 0 grams
Fats: 0 grams
Presentation: Package of 90 capsules.

CAFFEINE increases sports performance and mental concentration, while decreasing the feeling of fatigue and facilitating the burning of fat in the cells
Caffeine stimulates greater degradation of adrenaline and norepinephrine from the adrenal glands , in the same way as stimulants such as ephedrine, but their action is much less pronounced.
The ergogenic effects attributed to caffeine intake are based on 3 main mechanisms:
1º. Direct effect on the central and peripheral nervous system. Caffeine freely passes the cerebrovascular barrier, rapidly increasing its concentration in the nervous system after being ingested. In the brain, caffeine stimulates the elevation of several neurotransmitters such as serotonin, dopamine, acetylcholine, norepinephrine and glutamate, causing an increase in mental and motor activity. These effects are due to its antagonistic action of adenosine, which is a modulating neurotransmitter capable of affecting the release of other brain neurotransmitters, generally determining a loss of mental activity and motor activity. Caffeine determines a decrease in the subjective perception of fatigue and facilitates the propagation of nerve signals between the brain and the neuromuscular junction, because at a peripheral level, it enhances the release of acetylcholine in the motor endplate, inhibiting the action of adenosine also in muscle receptors, where they could block the release of acetylcholine, causing loss of strength. Caffeine prevents this effect and prolongs muscular work capacity.
2nd. Caffeine or its metabolite, hypoxanthine, inhibit phosphodiesterase, which is a muscle enzyme that, when activated, stops the breakdown of fat in the muscle cell, so if caffeine prevents or delays the activation of this enzyme, it allows it to be prolonged. the time for which fats can continue to be broken down as an energy source. Caffeine works by maintaining the levels of an intermediate, cyclic 3.5 AMP, which keeps active the enzyme that initiates the breakdown of fats, TGLHS, (triglyceridolipase sensitive to the lipolytic hormone action of catecholamines) and activates the conversion of another on top, phosphorylase, which accelerates the breakdown of glycogen, to its most active form "b", which increases the sensitivity of energy pathways and predisposes to make efforts more efficiently. This sensitizing effect is combined with an improvement in the ability to mobilize calcium from within the muscle fiber and its action to promote muscle contraction.
3rd. By improving the availability of fat and expanding its use as fuel, it protects glycogen levels, at least in the early phase of the exercise if the effort is maintained within intensities that allow adequate fat breakdown.
Another action of caffeine in the body is its ability to inhibit the action of antidiuretic hormones, such as ADH, acting as a diuretic agent (25). However, these effects are minimal and do not cause any effect on performance, when ingested in moderate amounts such as those normally used for habitual consumption of coffee or supplementation within the recommended doses.
“Caffeine is safe and legal for use in athletes when consumed in moderate amounts. Athletes should be educated about the effective dose of caffeine to enhance performance and the health dangers and counterproductive effects that excessive amounts can bring." Rosenbloom C. (2014).
Principal Interaction: Do not take the following combination!
Ephedrine interacts with caffeine. Stimulant drugs speed up the nervous system.Caffeine and ephedrine are stimulant drugs, so taking them together could cause a lot of stimulation and sometimes serious side effects and heart problems
Moderate Interaction: Use caution with this combination
Adenosine, Antibiotics, MAOIs, Alcohol, Birth Control Pills (decreases the rate of caffeine breakdown) and Diabetes Medications (decreases antidiabetic activity).
The combination of caffeine with 1,3-dimethylamylamine (DMAA), Citrus aurantium and Taurine may potentiate the incidence of acute heart attack. myocardium (Smith TB, et al. 2014 & Grasser EK, et al. 2014).
Directions for use: As a dietary supplement, take 1 tablet of 200 mg per day, preferably before training.
+ Assess sensitivity and tolerance to the product. Do not take at night.
+ It is not recommended to take more than 3 servings in less than 4 hours.
How is it taken?
One capsule (200 mg) in the morning as an energy intake for the whole day , and another capsule (200 mg) half an hour before training.
2 – 10 mg/Kg or more. However, excessive doses (more than 800 mg / day) can generate an increase in urine levels greater than 15 µg/mL, exceeding the limits established by the National Collegiate Athletic Association.